Ultrasonography is a sensitive tool for monitoring localized scleroderma

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Ultrasonography is a sensitive tool for monitoring localized scleroderma.

OBJECTIVE To examine the usefulness of ultrasonography (USG) for monitoring paediatric localized scleroderma (LS). METHODS A retrospective chart review of six paediatric patients who had USG of their LS. RESULTS USG detected several abnormalities in active lesions including increased blood flow, increased echogenicity and loss of subcutaneous fat. USG findings corresponded with clinical ass...

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Localized scleroderma is an autoimmune disorder.

OBJECTIVES There have been many studies suggesting that localized scleroderma has a strong autoimmune background, although the lesions are usually limited to the skin and subcutaneous tissue. Here we summarize previous data on the autoimmunity of localized scleroderma, mostly published in the last two decades, because there has not been a review paper summarizing autoimmunity in this disorder. ...

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Localized Scleroderma

Morphea (localized scleroderma) is an autoimmune disease characterized by sclerosis of the skin and, in some cases, subcutaneous tissue. It occurs in children and adults. It is distinct from systemic sclerosis, but may nevertheless be associated with significant functional and cosmetic impairment. Morphea has several distinct subtypes, including circumscribed, linear, and generalized, all of wh...

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Mycophenolate mofetil for localized scleroderma

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2007

ISSN: 1462-0324,1462-0332

DOI: 10.1093/rheumatology/kem120